Searchable abstracts of presentations at key conferences in endocrinology

ea0059p121 | Neoplasia, cancer & late effects | SFEBES2018

Progestin-induced breast cancer: Identifying the role of progesterone receptor isoforms

Cartwright Meghan , Louw-du Toit Renate , Africander Donita

Breast cancer is the most common oncology-related cause of death in women worldwide. The use of progestins in combined hormone replacement therapy (HRT) has been implicated in increasing the risk of developing breast cancer in postmenopausal women. Since various progestins are available for clinical use, all differentiated by structure, it is possible that not all progestins would lead to increased breast cancer risk. Progestins are synthetic ligands of the progesterone recept...